Transforming mRNA Manufacturing for the Next Generation of Medicine

The mRNA Revolution Faces a Critical Manufacturing Bottleneck
Batch reactions compromise mRNA integrity and generate contaminants, reducing therapeutic efficacy
Current manufacturing requires extensive purification that increases costs and extends timelines
Traditional manufacturing methods require extensive re-engineering to meet demand

Waterfall Scientific's
Fluidics Platform
01 Continuous Flow Synthesis
Our approach anchors both the DNA template and enzyme to a solid surface, creating a continuous stream of high-quality mRNA that prevents impurity formation at the source.

02 Cleaner, More Potent mRNA
By stopping unwanted byproducts during synthesis, we deliver higher-purity mRNA that translates to stronger performance in downstream applications.

03 Reduces Costs & Time
Eliminating impurities up front cuts heavy purification steps, streamlines the entire manufacturing process, and shortens timelines.

04 Enabling Seamless Scaling
Our uniform production process works consistently from discovery to GMP/commercial manufacturing, removing the need for costly, time-consuming redesign.

Meet our Team
Waterfall Accepted to The Engine's Fall 2025 Cohort


Our mission is to enable manufacturing of high-quality mRNA that accelerates therapeutics development from discovery to clinic and commercialization.
